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Finding the right R&D strategy is perhaps the most critical element in the future success of a pharmaceutical company. Throughout the R&D process a company needs to continually assess whether to continue or stop investigation of a compound.

 

Having identified possible candidates for further development, commercial assessment of their potential should to start early on. The candidates have to be compared regularly with others already launched on the market in terms of market penetration, potential usage and advantages, as well as those currently in the R&D pipeline. While current market assessment is valid, a longer term forecast is critical to see the likely shape and value of the market when products might ultimately be launched.

To determine likely market penetration, companies can also benchmark their drug candidates against products already on the market whose market positioning, degree of innovation and efficacy is similar.

As the compounds progress and their efficacy on specific disease areas become clearer, more sophisticated analysis of current treatments and prescribing patterns should be undertaken to determine the best dosage regimens, target market and potential prescribers.

As the level of investment increases so the impact of new R&D candidates on the whole portfolio is evaluated to see if the balance of the portfolio needs to be changed. This may manifest itself in possible divestiture of older products or licensing out some R&D candidates to concentrate on those with the best strategic fit.



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