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Positioning of Small Companies with the 'Megabrand' Scenario

A logical question to ask is, will the concept of megabrands spell death for smaller companies? Not according to Mr Rolf Stahel, CEO of Shire Pharmaceuticals.

Mr Stahel replied to IMS HEALTH, "Yes, the megabrand issue applies to the big multinationals since they function in the primary care market. However, 'megabrands' will not be an issue for generic and OTC companies (whose markets are different), and companies like Shire, the latter who function in the 'speciality' sector targeting specialists."

Mr Stahel explained that in the R&D setting the implications are different for large versus small companies. "Drugs with potential in the primary care setting are assessed in a much larger pool of people, and as trials progress, the efficacy as defined at an earlier discovery stage, in general is less dramatic and a parallel occurs in the side effect issue (i.e. more side effects are registered), with the result that these companies have to reassess their earlier estimates," stated Mr Stahel, "With smaller companies looking at more 'niche' areas, the research pool of patients is smaller, with the result that the efficacy and side effects estimates seen in the discovery phase tend to parallel much more readily those witnessed in late clinical testing. Megabrands will not kill off the smaller company."

For further details about Shire and its strategy, see IMS HEALTH's Pharmaceutical Company Profile, which includes more of the interview with the CEO.

01 Feb 2000, Copyright IMS HEALTH

See Also: Definition of Megabrand
Recent Blockbuster History
Therapeutic Categories offering Megabrand Potential
AstraZeneca's Potential Megabrands
The Trend Towards Megabrands
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